Drostanolone propionate is a DHT derivative, incapable of estrogen conversion, and a very popular pre-contest hardening drug. Medically, drostanolone use was primarily indicated for treatment of breast cancer prior to the introduction of newer aromatase inhibitors and not for protein sparing or muscle building purposes. As such, masteron seems to interact with estrogen receptors and may be a good addition to a stack simply for the purpose of preventing estrogen related side effects from other compounds. Drostanolone is a powerful androgen and therefore a good choice for adding hardness to an already lean physique. At low Drostanolone propionate doses there does not appear to be much suppression of the HPTA which adds to drostanolone's appeal.
Considered by many to be a cutting drug, masteron serves this purpose well and makes a perfectly good substitute for either trenbolone or methenolone. For maximum effectiveness during a cutting cycle doses of around 400-500 mgs/week seems appropriate. Traditionally, Drostanolone propionate is found with the propionate ester attached necessitating every other day injections. By combining both the enanthate and propionate esters users can achieve a more balanced blood concentration throughout a cycle with fewer injections, however, many will still prefer a EOD approach.
Drostanolone is a popular stacking compound and combines well with testosterone, boldenone, stanozolol and others. Some users report experience with dosages of 700 mg/week and more with good results however others claim little or no difference with lower doses.