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HCG Human Chorionic Gonadotropin
The Leydig cells of the testis possesess receptors which when stimulated by LH or HCG bring about activation of testosterone synthesis. This increase in synthesis is rapid, a 50% increase in plasma testosterone concentration has been measured 2 hours after intramuscular injection of 6000IU of HCG.
To stimulate ovulation, HCG is used in conjunction with FSH (follicle stimulating hormone) in infertile women. Occasionally, HCG is used to stimulate testicular hormone production when puberty is delayed.
The increasingly successful identification of anabolic steroid abusers by various IOC approved tests has led abusers to switch to testosterone abuse, which itself may be detected by measurement of the testosterone:epitestosterone ratio. Abuse of HCG has become popular because it stimulates the secretion from the testes of both testosterone and epitestosterone, resulting in a urinary excretion ratio of less than 6:1, below the limit set by the IOC. This led to the banning of HCG by the IOC in 1987.
A standard doping regime for HCG has been described (Brooks et al., 1989) in which the abuser firstly injects testosterone. Apart from any gains in strenght or competitiveness, the testosterone causes inhibition of LH secretion from the pituitary. When testosterone is withdrawn before competition (to avoid detection) the athlete would be at a disadvantage with lower that normal plasma testosterone levels. However, administration of HCG stimulates testicular testosterone secretion and also that of epitestosterone, so that apparent compliance with IOC regulations occurs. In a small, elgant experiment, Kicman, Brooks and Cowan (1991) have reproduced this situation in three normal men and shown that HCG can stimulate the testosterone substitution claimed by abusers and retain the testosterone/epitestosterone ratio within the IOC limits. In all three cases, the HCG could be detected in the urine by radioimmunosassay as long as plasma testosterone levels were raised. Despite the availability of a highly specific radioimmunosassay for HCG, it does not yet reproduce the discriminating power of gas chromatography and mass spectrometry and so it is as yet unaccepted by the IOC.
The side-effects of HCG will be similar to those described for anabolic steroids. However, the incidence of gynaecomastia may be greater as HCG also stimulates oestradiol production by the Leydig cells.
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Forget gym, steroids and other hulk protein can help muscles grow
MELBOURNE: If you hate the idea of hitting the gym, a new 'hulk' protein can help you achieve a toned and muscular look, scientists claim. Scientists in Australia say they have discovered one of the molecular keys to a protein that promotes weight and muscle mass gain, without any exercise involved like steroids. Researchers found that by blocking the function of Grb10, nicknamed the 'Hulk' protein , while mice were in the womb, they were considerably stronger and more muscular at birth than normal mice.
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Steroids for sale online become more and more popular and bodybuilders from all over the world use online steroids shops to buy steroids for their bodybuilding purposes. Steroids for sale are different physical enhancement drugs which helps people get success in weight lifting, in building their body and get stronger. Once you decided to buy steroids it means you are ready for this and that means a lot of reading and talking on different bodybuilding forums.
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Today, steroids are the most talked about products among sportspersons, particularly anabolic steroids. This is primarily because of detrimental effects that such products can have on one's body, if not taken as per doctor's prescription.
